AI Platform Market to Witness Increased Revenue Growth Owing to Rapid Increase in Demand – Market Reports

AI Platform Market to Witness Increased Revenue Growth Owing to Rapid Increase in Demand  Market Reports

AI Platform Market: Introduction. Decision making being one of the key points for the *service* providers and different manufacturers in the market has led to the …

“Sweden ai” – Google News

Guided by AI, robotic platform automates molecule manufacture

Guided by artificial intelligence and powered by a robotic platform, a system developed by MIT researchers moves a step closer to automating the production of small molecules that could be used in medicine, solar energy, and polymer chemistry.

The system, described in the August 8 issue of Science, could free up bench chemists from a variety of routine and time-consuming tasks, and may suggest possibilities for how to make new molecular compounds, according to the study co-leaders Klavs F. Jensen, the Warren K. Lewis Professor of Chemical Engineering, and Timothy F. Jamison, the Robert R. Taylor Professor of Chemistry and associate provost at MIT.

The technology “has the promise to help people cut out all the tedious parts of molecule building,” including looking up potential reaction pathways and building the components of a molecular assembly line each time a new molecule is produced, says Jensen.

“And as a chemist, it may give you inspirations for new reactions that you hadn’t thought about before,” he adds.

Other MIT authors on the Science paper include Connor W. Coley, Dale A. Thomas III, Justin A. M. Lummiss, Jonathan N. Jaworski, Christopher P. Breen, Victor Schultz, Travis Hart, Joshua S. Fishman, Luke Rogers, Hanyu Gao, Robert W. Hicklin, Pieter P. Plehiers, Joshua Byington, John S. Piotti, William H. Green, and A. John Hart.

From inspiration to recipe to finished product

The new system combines three main steps. First, software guided by artificial intelligence suggests a route for synthesizing a molecule, then expert chemists review this route and refine it into a chemical “recipe,” and finally the recipe is sent to a robotic platform that automatically assembles the hardware and performs the reactions that build the molecule.

Coley and his colleagues have been working for more than three years to develop the open-source software suite that suggests and prioritizes possible synthesis routes. At the heart of the software are several neural network models, which the researchers trained on millions of previously published chemical reactions drawn from the Reaxys and U.S. Patent and Trademark Office databases. The software uses these data to identify the reaction transformations and conditions that it believes will be suitable for building a new compound.

“It helps makes high-level decisions about what kinds of intermediates and starting materials to use, and then slightly more detailed analyses about what conditions you might want to use and if those reactions are likely to be successful,” says Coley.

“One of the primary motivations behind the design of the software is that it doesn’t just give you suggestions for molecules we know about or reactions we know about,” he notes. “It can generalize to new molecules that have never been made.”

Chemists then review the suggested synthesis routes produced by the software to build a more complete recipe for the target molecule. The chemists sometimes need to perform lab experiments or tinker with reagent concentrations and reaction temperatures, among other changes.

“They take some of the inspiration from the AI and convert that into an executable recipe file, largely because the chemical literature at present does not have enough information to move directly from inspiration to execution on an automated system,” Jamison says.

The final recipe is then loaded on to a platform where a robotic arm assembles modular reactors, separators, and other processing units into a continuous flow path, connecting pumps and lines that bring in the molecular ingredients.

“You load the recipe — that’s what controls the robotic platform — you load the reagents on, and press go, and that allows you to generate the molecule of interest,” says Thomas. “And then when it’s completed, it flushes the system and you can load the next set of reagents and recipe, and allow it to run.”

Unlike the continuous flow system the researchers presented last year, which had to be manually configured after each synthesis, the new system is entirely configured by the robotic platform.

“This gives us the ability to sequence one molecule after another, as well as generate a library of molecules on the system, autonomously,” says Jensen.

The design for the platform, which is about two cubic meters in size — slightly smaller than a standard chemical fume hood — resembles a telephone switchboard and operator system that moves connections between the modules on the platform.

“The robotic arm is what allowed us to manipulate the fluidic paths, which reduced the number of process modules and fluidic complexity of the system, and by reducing the fluidic complexity we can increase the molecular complexity,” says Thomas. “That allowed us to add additional reaction steps and expand the set of reactions that could be completed on the system within a relatively small footprint.”

Toward full automation

The researchers tested the full system by creating 15 different medicinal small molecules of different synthesis complexity, with processes taking anywhere between two hours for the simplest creations to about 68 hours for manufacturing multiple compounds.

The team synthesized a variety of compounds: aspirin and the antibiotic secnidazole in back-to-back processes; the painkiller lidocaine and the antianxiety drug diazepam in back-to-back processes using a common feedstock of reagents; the blood thinner warfarin and the Parkinson’s disease drug safinamide, to show how the software could design compounds with similar molecular components but differing 3-D structures; and a family of five ACE inhibitor drugs and a family of four nonsteroidal anti-inflammatory drugs.

“I’m particularly proud of the diversity of the chemistry and the kinds of different chemical reactions,” says Jamison, who said the system handled about 30 different reactions compared to about 12 different reactions in the previous continuous flow system.

“We are really trying to close the gap between idea generation from these programs and what it takes to actually run a synthesis,” says Coley. “We hope that next-generation systems will increase further the fraction of time and effort that scientists can focus their efforts on creativity and design.”  

The research was supported, in part, by the U.S. Defense Advanced Research Projects Agency (DARPA) Make-It program.

MIT News – Artificial intelligence

Point & Place® Augmented Reality Shopping Platform Adds WebAR Syndication to Expand the Retail Network to Over 600 Retailers, Across 70 Countries content= – PR Newswire UK

Point & Place® Augmented Reality Shopping Platform Adds WebAR Syndication to Expand the Retail Network to Over 600 Retailers, Across 70 Countries content=  PR Newswire UK

LONDON, Aug. 5, 2019 /PRNewswire/ — Today, Eyekandy Ltd announced the mainstream adoption of AR shopping with the launch of an additional WebAR …

“augmented reality” – Google News

Every Single Sex Toy in Third Aurora’s Augmented Reality Platform – Yahoo Finance

Every Single Sex Toy in Third Aurora’s Augmented Reality Platform  Yahoo Finance

Couples View Bondage Gear, Sex Toys In The Home. GEELONG, Australia, Aug. 6, 2019 /PRNewswire/ — Inquisitive couples who are “eager to try, but simply …

“augmented reality” – Google News

BlockV Platform is Using Blockchain to Bring Vatoms to Life, Creating a Whole New Augmented Experience – The Merkle Hash

BlockV Platform is Using Blockchain to Bring Vatoms to Life, Creating a Whole New Augmented Experience  The Merkle Hash

6th August 2019, Zug Switzerland – As our world evolves into an age of mixed, virtual and augmented reality, new kinds of human experience become possible …

“augmented reality” – Google News

Every Single Sex Toy in Third Aurora’s Augmented Reality Platform – PRNewswire

Every Single Sex Toy in Third Aurora’s Augmented Reality Platform  PRNewswire

GEELONG, Australia, Aug. 6, 2019 /PRNewswire/ — Inquisitive couples who are “eager to try, but simply too shy” can now view items such as bondage cages, …

“augmented reality” – Google News

Point & Place® Augmented Reality Shopping Platform Adds WebAR Syndication to Expand the Retail Network to Over 600 Retailers, Across 70 Countries – PRNewswire

Point & Place® Augmented Reality Shopping Platform Adds WebAR Syndication to Expand the Retail Network to Over 600 Retailers, Across 70 Countries  PRNewswire

LONDON, Aug. 5, 2019 /PRNewswire/ — Today, Eyekandy Ltd announced the mainstream adoption of AR shopping with the launch of an additional WebAR …

“augmented reality” – Google News

Point & Place® Augmented Reality Shopping Platform Adds WebAR Syndication to Expand the Retail Network to Over 600 Retailers, Across 70 Countries – Yahoo Finance

Point & Place® Augmented Reality Shopping Platform Adds WebAR Syndication to Expand the Retail Network to Over 600 Retailers, Across 70 Countries  Yahoo Finance

LONDON, Aug. 5, 2019 /PRNewswire/ — Today, Eyekandy Ltd announced the mainstream adoption of AR shopping with the launch of an additional WebAR …

“augmented reality” – Google News

Swedish taxi platform selects Here as mapping and location services provider – Traffic Technology Today

Swedish taxi platform selects Here as mapping and location services provider  Traffic Technology Today

A Scandinavian company that has developed a technology platform that matches riders to drivers for more than 60,000 taxi trips every day, has switched to …

“Sweden ev” – Google News

US Navy tests TRACER augmented reality combat training platform – Naval Technology

US Navy tests TRACER augmented reality combat training platform  Naval Technology

The US Navy has tested a platform based on augmented reality (AR) that is designed to significantly improve combat training. The platform is sponsored by the …

“augmented reality” – Google News